New Advances in Dye Analyses: In Situ Gel-Supported Liquid Extraction from Paint Layers and Textiles for SERS and HPLC-MS/MS Identification

To date, it is still not possible to obtain exhaustive information about organic materials in cultural heritage without sampling. Nonetheless, when studying unique objects with invaluable artistic or historical significance, preserving their integrity a priority. In particular, dye identification of significant interest for history and conservation research, but hindered by analytes’ low concentration poor fastness. this work, minimally invasive approach presented. The procedure designed accompany noninvasive analyses inorganic substances comprehensive studies complex matrices, compliance soundness. Liquid extraction madder, turmeric, indigo dyes was performed directly from paint layers textiles. supported hydrogels, which themselves can undergo multitechnique the place samples. After extraction, Ag colloid pastes were applied on gels SERS analyses, allowing three dyes. For HPLC-MS/MS re-extraction followed clean-up step that successfully madder turmeric. colour change perceptivity after measured colorimetry. results showed ΔE values mostly below upper limit rigorous change, confirming gentleness procedure.